Discussion 'New treatments'
Understanding Lecithin Cholesterol Acyltransferase (LCAT) Deficiency Disorders
Lecithin cholesterol acyltransferase (LCAT) deficiency is a genetic disorder that affects the body's ability to process cholesterol. It is characterized by cloudiness of the clear front surface of the eye (corneal opacities), a shortage of red blood cells (hemolytic anemia),…
Understanding the Effects of Space Missions on Human Health and Behavior
Space scientists speculate that we will likely set foot on mars in the next two decades, yet we know little about how our brains and bodies change and respond to the space environment and the use of medications that go…
Beyond CAR-T: Re-engineering Cells into Life-saving Therapies
Our cells have the innate ability to protect us. The idea of using cells as medicine emerged with bone marrow transplants, and then CAR-T therapy for blood cancers. Now, scientists are beginning to engineer much more complex living therapeutics by…
Diagnosis and Management of Waldenstrom’s Macroglobulinemia
Waldenstrom's macroglobulinemia (WM) is a rare type of cancer that begins in the white blood cells.The abnormal white blood cells produce a protein that accumulates in the blood, impairs circulation and causes complications. It continues to be a clinical challenge…
Evolving Treatment Paradigm of Multiple Myeloma
In the past decade, the FDA has approved 13 new agents and 29 treatments for multiple myeloma, which have transformed the treatment paradigm for patients. The expanded treatment options have resulted in significantly improved outcomes. Two decades ago, the median…