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Drug Repurposing for COVID-19 with CORONA Registry (COvid 19 Registry of Off-label & New Agents)
The global crisis due to COVID19 and the urgent need to identify effective therapeutics prompted Dr. David Fajgenbaum from the University of Pennsylvania and his research team to create a database that tracks every off-label and experimental drug being used…
Evolving Treatment Paradigm of Multiple Myeloma
In the past decade, the FDA has approved 13 new agents and 29 treatments for multiple myeloma, which have transformed the treatment paradigm for patients. The expanded treatment options have resulted in significantly improved outcomes. Two decades ago, the median…
Developments in Personalized Medicine and New Options in Breast Cancer Treatment
In this era of personalized medicine the standard "one dose fits all" approach to cancer care has been ineffective leading to treatment failures. Personalized medicine is a new healthcare paradigm that allows physicians to choose treatment methodology optimally based on…
Understanding Lecithin Cholesterol Acyltransferase (LCAT) Deficiency Disorders
Lecithin cholesterol acyltransferase (LCAT) deficiency is a genetic disorder that affects the body's ability to process cholesterol. It is characterized by cloudiness of the clear front surface of the eye (corneal opacities), a shortage of red blood cells (hemolytic anemia),…
Early Age Onset Colorectal Cancer – Trends and Challenges
Colorectal cancer is a term that includes colon and rectal cancers, both of which originate in the lower portion of the large intestine and into the rectum. Colorectal cancer (CRC) incidence in the United States is declining rapidly overall but,…